Research Portfolio

Infection and Antibiotic Resistance
Rehabilitation / Long Term Conditions / Chronic Conditions
Health Communication and Behaviour Change
Effectiveness of Interventions / Quality of Care
Domestic Abuse
Cancer in Primary Care
Community Research Nursing


Project Title Project acronym Principle Investigator Status Type of Study Funder Total Value
Bath Additives in the Treatment of cHildhood Eczema BATHE Dr Nick Francis Active RCT NIHR £959,00
Blood Stream Infections: Focus on outcomes Prof Chris Butler Ongoing Research for Patient Benefit Program NIHR £2,054,768
Centre of Research Excellence in Minimising Antibiotic Resistance for Acute Respiratory Infections CREMARA Prof Chris Butler (Led by Bond University, Australia) Active Infrastructure NHMRC Centres of Research Excellence(Australian Government) $2.5M (Australian $)
ChildRen with Eczema Antiobiotic Management Study CREAM Dr Nick Francis Active RCT NIHR HTA £1,333,027
Common infections, their complications, antibiotic prescribing and resistance: Moving away from simple correlations Prof Chris Butler Completed Fellowship DoH £160,118
Development of RApid Point-of-Care test Platform for Infectious Diseases RAPP-ID Jorge Villacian Active Developmental Innovative Medicines Initiative £12,776,340
Development of Polymerase Chain Reaction (PCR) methods for the laboratory identification and analysis of urinary tract infections PCR Methods Dr Nick Francis Completed Laboratory Wellcome Trust / NISCHR / Cardiff University – Seed corn £50,000
Improving virucidal activity of surface disinfectant formulations J Mallard Completed Grouo AC Marca SL £250,662
GRACE-INTRO (Genomics to combat Resistance against Antibiotics for Community acquired LRTI in Europe) (INternet Training for Reducing antibiOtic use) Trial. GRACE-INTRO Prof Paul Little Completed Interventional EU FP7 £70,943
Oral Steroids for Resolution of Otitis Media with Effusion (OME) In CHildren: the OSTRICH study OSTRICH Dr Nick Francis and Prof Chris Butler Active RCT NIHR HTA £1,083,208
Probiotics for Antibiotic Associated Diarrhoea, including Clostridium difficile, in care homes: Establishing the platform and a randomised controlled trial PAAD Prof Chris Butler Completed RCT NIHR HTA £1,759,010
Platform foR European Preparedness Against (Re-)emerging Epidemics PREPARE Prof Chris Butler Active Numerous work packages FP7 £2,271,863
Resistance in Gram Negative Bacteria R-GNOSIS Marc Bonten Active Observational and RCT EU FP7 £9,701,865 (€11,999,999)
Stemming the tide of antibiotic resistance: A trial of complex intervention addressing the 'why' and 'how' of appropriate antibiotic prescribing in general practices STAR Prof Chris Butler Completed Educational Programme MRC £523,500
The Diagnosis of Urinary Tract Infections in Young Children Study DUTY Prof C. Butler and Dr A. Hay Completed Observational NIHR HTA £3,255,155
The epidemiology of Urinary Tract Infection (UTI) in children with acute illness in primary care EURICA Dr Kathryn O'Brien Completed Observational Pilot Study WORD £139,897
Translating the epidemiology of health care associated infections and antibiotic resistance into improved clinical care, ARCHIE Prof Chris Butler Completed Observational National Assembly for Wales £233,518
Understanding and responding to challenges in the diagnosis and management of cellulitis in primary care. EASI-PC Dr Nick Francis Ongoing Modelling routine data NISCHR Health Fellowship (Dr Nick Francis) £251,447
Can community supported exercise benefit subjective wellbeing, pjysical activity levels and abilities in people with Huntington's disease? A randomised feasibility study and process evaluation. COMMET-HD Dr Monica Busse-Morris Completed RCT WAG (RFS Health Research Award) £122,720
Caring for adult patients with acute exacerbations of asthma or COPD in general practice PEXACO Hasse Melbye Completed Qualitative Focus Group Research Council of Norway £29,031
Fracture in the Elderly Multidisciplinary Rehabilitation FEMuR Dr Nefyn Williams Active Sys Review NIHR HTA £519,537
Management strategies for sciatica Dr Nefyn Williams Completed Systematic Review NIHR HTA £258,234
The Functional Recovery from stroke during rehabilitation in the Cardiff Stroke Unit and home environment. Dr Robert van Deursen Completed Randomised feasibility study and process evaluation NISCHR £60,000
Changing behaviour of health care professionals and the general public towards a more prudent use of antimicrobial agents CHAMP T. Verheij and Prof C. Butler Completed Scenario based questionnaire study / multicentre qualitative study Commission of European Communities £952,080
Enhancing the quality of Information-sharing in primary care for childhood respiratory tract infections EQUIP Prof Chris Butler Completed Fellowship MRC £298,152
Exploring the transition from relapsing-remitting to secondary progressive multiple sclerosis MS Study Prof Adrian Edwards Active Qualitative MS Trust £49,960
Preventing disease through opportunistic, rapid engagement by primary care teams using behaviour change counselling PRE-EMPT Prof Chris Butler Completed Cluster Randomised Trial MRC/NPRI £809,267
MAking Good Decisions In Collaboration with patients / Shared Decision Making MAGIC Prof Glyn Elwyn Active Observational Health Foundation £354,055
Weight loss maintenance in adults WILMA Dr SA Simpson Active RCT NIHR HTA £1,479,762
Centre for the Improvement of Population Health through E-health Research CIPHER RA Lyons Active Infrastructure MRC / NISCHR £4,373,292
Development of antimicrobial restorative materials to manage dental disease in older adults. Dr Christopher Lynch Completed Development of new material The Dunhill Medical Trust £49,138
Intervention Now to Eliminate Repeat Unintended Pregnancies in Teenagers INTERUPT Rhiannon Whitaker Active Systematic review NIHR HTA £196,093
Interventions to reduce unplanned hospital admissions S Purdy Completed Systematic review NIHR SDO £85,934
Seal or Varnish? A randomised trial to determine the relative cost and effectiveness of pit and fissure sealants and fluoride varnish in preventing dental decay. Seal or Varnish Prof Ivor G. Chestnutt Active RCT (IMP) NIHR HTA £1,380,073
Development of an evaluation framework to analyse the impact Home-Start support has for families facing complex and multiple difficulties, including domestic abuse. Home-Start Evaluation Prof Joyce Kenkre Active Evaluation LanKelly Chase Foundation in collaboration with HomeStart UK £40,000
An investigation of the effect of choral singing on quality of life in patients previously diagnosed with cancer, and their carers Prof Robert Van Deursen Active Intervention Tenovus £1,775
Centre for the Improvement of Population Health through E-health Research CIPHER RA Lyons Active Infrastructure Medical Research Council/NISCHR £4,373,292
Development and evaluation of a set of core human papilloma virus (HPV) messages to promote informed choice HPV Messages Prof Clare Wilkinson Completed Observational - cohort Cancer Research UK £258,771
Development of scripts for use in consultations for HPV tested women HPV Scripts Prof Clare Wilkinson Active Qualitative Tenovus £30,000
Diagnostic journeys in myeloma (DJiM) DJiM Tania Seale, RD Neal Active Qualitative Tenovus £60,000
Effectiveness and cost-effectiveness of patient education media about physical activity promotion among adult cancer survivors Dr Sadia Nafees / Prof Clare Wilkinson Completed Pilot RCT BCUHB £17,150
Improved Lung Cancer Identification by targeted chest X-ray ELCID Prof Richard Neal Active RCT NIHR HTA £380,000
International Cancer Benchmarking Partnership: Module 4 For Wales ICBP4 Prof Richard Neal Active RCT Cancer Research Wales £114,000
Phillips Blood Count Phillips Blood Count Prof Richard Neal Active Qualitative Tenovus £29,827
The Role of Exercise in patients with cancer cachexia: A study of preferences, motivation and outcomes of importance in patients with advanced cancer Dr Anthony Byrne Completed Randomised feasibility study and process evaluation Tenovus £29,956
TOPCAT-G TOPCAT-G Simson Leeson Active Randomised feasibility study Betsi Cadwaladr University Health Board £70,000
TOPCAT-P TOPCAT-P Prof Clare Wilkinson Active RCT Macmillan £297,397
Talking about HPV-related cancer: Developing and testing scripted consultations after HPV-related cancer diagnosis HPV-related cancer Prof Clare Wilkinson Active Qualitative NISCHR-RfPB £228,000
Building Blocks. Evaluating the family nurse partnership programme in England: A randomised controlled trial Building Blocks Dr Mike Robling Completed Policy Research DoH PRP £4,984,040
Building Blocks follow-on study Building Blocks follow-on Dr Mike Robling Active Service evaluation DoH PRP £646,014